Mouse model of portopulmonary hypertension

What is it about?

Here we show evidence that mice that have developed cirrhosis due to carbon tetrachloride exposure develop blood vessel changes in the lung that are analagous to the human condition known as portopulmonary hypertension.

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Why is it important?

This is the first report of a mouse model for portopulmonary hypertension. Advances against this disease are unlikely without such a model.