What is it about?
This is a short article describing OpenZika - an IBM World Community Grid project. It describes why we are trying to identify antivirals using docking in all the crystal structures and homology models from the Zika virus. It provides information on all the proteins we are looking at in addition we arre docking millions of compounds in related flavivirus structures.
Why is it important?
The Zika virus has become an importan public health challenge in the Americas and elsewhere. Currently there is no vaccine and the need to find antivirals that are safe to pregnant women is urgent. The images of microcephally have caused concern globally.
The following have contributed to this page: Dr Sean Ekins