What is it about?

Fetal membranes that surround the amniotic cavity retain amniotic fluid, secrete substances, and protect the fetus from infection. Pre-labor rupture of membranes (PROM) is the rupture of fetal membranes after 28 weeks of gestation but before the onset of labor. A preterm premature rupture of membranes (PPROM) occurs before 37 weeks of gestation and term PROM after 37 weeks of gestation. PROM is found in 3-15% of all pregnancies and 30-40% of preterm labors worldwide. Prematurity is the leading cause of perinatal morbidity and mortality in PPROM. The most serious complications are neonatal and prenatal mortality, which is higher in Africa, particularly in Ethiopia.

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Why is it important?

The magnitude of the pre-labor rupture of the membrane was higher than in previous studies. Therefore, all concerned bodies will emphasize low socioeconomic status, strengthen counseling, early diagnosis and treatment of infections, and gynecologic and clinical risks of pregnant mothers to reduce rupture of membranes and improve fetal and perinatal health.

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This page is a summary of: Pre-labor rupture of membranes and associated factors among pregnant women admitted to the maternity ward, Northwest Ethiopia, PLOS Global Public Health, March 2023, PLOS,
DOI: 10.1371/journal.pgph.0001702.
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