What is it about?
Conjugation is a method of genomic transfer between bacteria. In nature, conjugation allows for transfer of antibiotic resistance genes and virulence factors. We have developed a method in the lab to reproduce these exchanges and found a surprising diversity in recombined fragments sizes and lengths.
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Why is it important?
Our findings show that there is an heterogeneity in recombination patterns linked to the phylogenetic distance between the donor and the recipient. Moreover, our method enabled us to pinpoint the precise location in the recombinant of the loci under selection.
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This page is a summary of: High-throughput conjugation reveals strain specific recombination patterns enabling precise trait mapping in Escherichia coli, PLoS Genetics, October 2025, PLOS,
DOI: 10.1371/journal.pgen.1011636.
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