What is it about?

It is well known that (AKI) is common in coronavirus disease-2019 (COVID-19) and associated with poor prognosis. In this multicenter and observational study, we document patient and renal outcomes according to acute kidney injury (AKI) stages in hospitalized patients with AKI and COVID-19. It also comprehensively covers risk factors associated with the patient and renal outcomes in different stages of AKI in a relatively large sample in a comparative manner.

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Why is it important?

We found that In-hospital mortality rates are high in AKI patients with COVID-19, and severe stages of AKI are associated with worse patient outcomes. Renal outcomes are worsening if the patient has pre-existing CKD or AKI stage 3. The risk factors reportedly associated with mortality in patients with COVID-19, such as older age, male gender, and comorbidities, including diabetes mellitus, were also valid among patients with COVID-19 and AKI. The impact of the severity of AKI and/or COVID-19 on mortality appears to be greater than the potential negative impact of pre-existing chronic kidney disease.

Perspectives

While healthcare professionals in y country and all over the world are struggling with COVID-19, I was very motivated as a nephrologist when all my colleagues in my country recorded the data during a period when they were working hard in hospitals. The unconditional support this by the Turkish Society of Nephrology was also commendable.

Hakki Arikan
Marmara Universitesi

Read the Original

This page is a summary of: Characteristics and outcomes of acute kidney injury in hospitalized COVID-19 patients: A multicenter study by the Turkish society of nephrology, PLoS ONE, August 2021, PLOS,
DOI: 10.1371/journal.pone.0256023.
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