What is it about?
We have used data from the Swedish Obese Subjects (SOS) study; ClinicalTrials.gov, identifier: NCT01479452 – a prospective controlled intervention study examining weight-loss surgery outcomes – to examine the impact of weight loss surgery on the long-term risk of colorectal cancer. In our study, we could not verify that weight-loss surgery leads to changes in colorectal cancer risk in patients with obesity. Our results rather indicates a possible decreased risk of rectal cancer with weight-loss surgery.
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Why is it important?
Obesity is a risk factor for several types of cancer, and intentional weight loss sometimes reduces the risk. Although weight-loss surgery is considered to reduce cancer risk in general, whether the incidence of colorectal cancer increases or decreases after this treatment is debated.
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This page is a summary of: Long-term incidence of colorectal cancer after bariatric surgery or usual care in the Swedish Obese Subjects study, PLoS ONE, March 2021, PLOS,
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