What is it about?

Autism Is associated with many co-occurring conditions that involve other organs, but much of the research has been focused on the brain. Using public databases, this study found that genes associated with autism and co-morbidities were expressed not just in the brain, but in other organs.

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Why is it important?

This paper demonstrates that genes associated with autism are present in other organs outside of the brain. The paper also reinforces the evidence that highly interconnected molecular pathways are involved across the body and would benefit from further investigation in how these organs might be impacted, as co-occurring conditions such as stomach problems can impact quality of life.

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This page is a summary of: Coupling of autism genes to tissue-wide expression and dysfunction of synapse, calcium signalling and transcriptional regulation, PLoS ONE, December 2020, PLOS,
DOI: 10.1371/journal.pone.0242773.
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