What is it about?

We created a universal theoretical modeling framework for pathogen transmission based on rigorous metapopulation theory in ecology.

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Why is it important?

This patch dynamics modeling framework seamlessly integrates pathogen, host, and environment, the three most important components in epidemiological triad. It offers a unified framework to integrate both within-host infection and between-host transmission processes.


This is an innovative modeling framework to complement and significantly expand the century-old SEIR-type compartment epidemic models. The compartment models are a special case of the more universal patch dynamics model described in this paper.

Shi Chen
University of North Carolina at Charlotte

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This page is a summary of: Patch dynamics modeling framework from pathogens’ perspective: Unified and standardized approach for complicated epidemic systems, PLoS ONE, October 2020, PLOS, DOI: 10.1371/journal.pone.0238186.
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