What is it about?

This study is about the changes in the retina (the sensory tissue in the eye responsible for vision) seen in cerebral malaria. Cerebral malaria is a severe complication of malaria which affects the brain and often results in death. We have shown that, in patients who died from malaria, changes in the eye are strongly associated with changes in the brain. Patients who died in whom an alternative diagnosis was found often had illnesses affecting the lungs, liver and brain.

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Why is it important?

This work has helped us to create a treatment protocol which can be applied in both high- and low-resource settings.

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This page is a summary of: Re-evaluating malarial retinopathy to improve its diagnostic accuracy in paediatric cerebral malaria: A retrospective study, PLoS Medicine, September 2025, PLOS,
DOI: 10.1371/journal.pmed.1004727.
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