What is it about?

Arthritis causes inflammation of the joint lining. Receptors in the joint lining respond to chemical messengers released in the joint and convey the sensation of pain via nerves to the brain. This article explains an important area of this process, mediated by a molecule called nerve growth factor (NGF). New therapies are able to block the action of NGF and so provide relief from pain in arthritis.

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Why is it important?

Therapies blocking NGF are now available for dogs (Europe) and cats (Europe and USA)


These therapies are the biggest change in medical management of osteoarthritis in a generation.

Professor John Innes
University of Liverpool

Read the Original

This page is a summary of: Understanding and managing pain in the arthritic synovial joint: an update, Companion Animal, January 2022, Mark Allen Group, DOI: 10.12968/coan.2021.0036.
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