What is it about?

Guidelines suggest treating incidental PE as symptomatic PE in patients with cancer, but the outcomes in cancer patients with incidental PE are not well known. We used the data from the RIETE registry to compare the 3-month outcomes in patients with active cancer and incidental PE vs. those with clinically-suspected and confirmed PE.

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Why is it important?

We enrolled 946 cancer patients with incidental asymptomatic PE and 2,274 with clinically-suspected and confirmed PE. In this study, the risk for VTE recurrences or major bleeding was similar. Patients with incidental PE had a lower mortality risk.


While caution should be exercised in interpretation of the results, our findings may have implication for treatment strategies, including among patients with highest risk of complications from antithrombotic therapy. The optimal management strategy for these patients should be tested in future randomized trials.

Juan José López-Núñez

Read the Original

This page is a summary of: Clinical characteristics and 3-month outcomes in cancer patients with incidental versus clinically suspected and confirmed pulmonary embolism, European Respiratory Journal, December 2020, European Respiratory Society (ERS),
DOI: 10.1183/13993003.02723-2020.
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