What is it about?
• This study aimed to investigate the potential of peptides derived from quinoa seed proteins as multi-target antagonists against SARS-CoV-2, which is a virus that causes severe acute respiratory syndrome. • The seven identified peptides were predicted to interact with key binding residues and catalytic residues on three viral targets: spike glycoprotein receptor domain, main protease (M pro) and papain like protease (PL pro). • These interactions could potentially block entry of the virus into host cells and suppress its replication.
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Why is it important?
It is important to identify potential peptides that can act as multi-target antagonists against SARS-CoV-2, since this virus has caused a global pandemic. The seven identified peptides could potentially be used in drug discovery and development for the treatment of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2).
Read the Original
This page is a summary of: In Silico Identification of Multi-target Anti-SARS-CoV-2 Peptides from Quinoa Seed Proteins, International Journal of Peptide Research and Therapeutics, April 2021, Springer Science + Business Media, DOI: 10.1007/s10989-021-10214-y.
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