What is it about?
The paper talks about the effect on immune response of the cytokine IL-12 when administered to gerbil with sporotrichosis (a fungal infection).
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Why is it important?
We found that IL-12 increases Th1 response and improves sporotrichosis clearance. This is of importance for people working with cytokine teraphy for infectious disease, specially for those caused by fungal pathogens.
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This page is a summary of: Recombinant murine IL-12 promotes a protective Th1/cellular response in Mongolian gerbils infected withSporothrix schenckii, Journal of Chemotherapy, February 2014, Taylor & Francis,
DOI: 10.1179/1973947814y.0000000174.
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