What is it about?
It has generally been assumed that mycobacteria killing depends on the participation of immune cells, but we have shown that also cell-free plasma exhibits a strong mycobactericidal activity.
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Why is it important?
Serum is the usual supplement used for in vitro infection of human cells with Mycobacterium tuberculosis. We show that, unlike plasma, it has little mycobactericidal activity, which may explain why it has been traditionally so difficult to obtain killing activity in vitro.
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This page is a summary of: RETRACTED: Plasma contributes to the antimicrobial activity of whole blood against Mycobacterium tuberculosis, Innate Immunity, August 2016, SAGE Publications,
DOI: 10.1177/1753425916663311.
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