Adversity designation for veterinary pathologists

What is it about?

Authors provide additional context behind the process of adversity designation in their commentary on the article “Opinion on Designation of Adverse and Nonadverse Histopathological Findings in Toxicity Studies: The Pathologist’s Dilemma,”. Given that adversity designation can significantly impact the no observed adverse effect level and clinical trial design, it is important to carefully consider all of the criteria by which such assignments are made. Authors caution against reliance solely on histopathology for adversity designation providing perspective on how context beyond histopathology often plays a critical role in adversity designation.

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