What is it about?
Lenvatinib induces proteinuria and one of its etiology is thrombotic microangiopathy.
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Why is it important?
Long term use of multi-targeted kinase inhibitor, including lenvatinib, sometimes cause severe proteinuria and renal impairment.
Perspectives
We have to be aware of thrombotic microangiopathy in case of long term use of multi-targeted kinase inhibitor for RAI-refractory differentiated thyroid cancer.
Naomi Kiyota
Kobe University Hospital
Read the Original
This page is a summary of: Thrombotic Microangiopathy with Severe Proteinuria Induced by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Carcinoma, Case Reports in Oncology, November 2018, Karger Publishers,
DOI: 10.1159/000494080.
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