All Stories

  1. Encorafenib plus binimetinib for BRAF V600-mutated thyroid cancer in Japan: final analysis
  2. Long-Term Follow-Up of JCOG1008, a Randomized Phase II/III Trial of Chemoradiotherapy Comparing 3-Weekly Cisplatin With Weekly Cisplatin in Postoperative Head and Neck Cancer
  3. Current status and future perspectives of treatment de-escalation in localized head and neck cancer
  4. Risk factors for aspiration pneumonia related to postoperative chemoradiotherapy for high-risk head and neck cancer: A supplementary analysis of a phase II/III JCOG1008 trial
  5. Quality of Life Remained Stable with Encorafenib and Binimetinib in Thyroid Cancer
  6. Neoadjuvant FOLFOXIRI plus bevacizumab without radiotherapy for high-risk rectal cancer: multicentre phase II trial
  7. Nivolumab for platinum refractory salivary gland cancer
  8. Adverse event profiles and management of cisplatin-based chemoradiotherapy in locally advanced head and neck squamous cell carcinoma: a systematic review
  9. Corrigendum to: A Phase 2 Study of Encorafenib in Combination with Binimetinib in Patients with Metastatic BRAF -Mutated Thyroid Cancer in Japan
  10. A Cautious View on Reduced-Dose Neck Radiation in Head and Neck Cancer
  11. Trastuzumab plus docetaxel is an effective treatment option for HER2 positive salivary gland cancer.
  12. Current treatment options and development for anaplastic thyroid cancer (ATC).
  13. Can Weekly Symptom Monitoring Improve Outcomes for Patients with Advanced Cancer?
  14. Indications for chemoradiotherapy in elderly patients with locally advanced head and neck cancer.
  15. This the updated Japanese guidline for the management of thyroid cancer patients
  16. Retrospective study of definitive therapy for head and neck mucosal melanoma: The RESUME study
  17. Patients with head and neck cancer unfit for cisplatin—what next?
  18. The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer
  19. The european organisation for research and treatment of cancer head and neck cancer module (EORTC QLQ-HN43): Estimates for minimal important difference and minimal important change
  20. Incidence of hypothyroidism after postoperative chemoradiotherapy for head and neck cancer.
  21. Tumor immune microenvironment (TIME) in salivary gand cancer (SGC).
  22. Acute kidney injury impacted the OS for HNSCC patients undergoing postoperative chemoradiotherapy
  23. A risk prediction for cisplatin induced acute kidney injury in JCOG1008
  24. paclitaxel plus cetuximab for double refractory RMHNSCC
  25. Patient-Reported Outcomes in Randomized Controlled Trials for Cancer Conducted in Japan
  26. Targeting Anterior Commissure Involvement with Hyperfractionated Radiotherapy for T1–T2 Squamous Cell Carcinoma of the Glottic Larynx
  27. Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database
  28. Encorafenib/binimetinib should be another treatment option for BRAF mutated thyroid cancer patients.
  29. Post operative treatment for locally advanced squamous cell carcinoma of head and neck.
  30. Long‐term health‐related quality of life in head and neck cancer survivors: A large multinational study
  31. The impact of electronic versus paper-based data capture on data collection logistics and on missing scores in thyroid cancer patients
  32. Different characteristics of the tumor immune microenvironment among subtypes of salivary gland cancer
  33. Summary of Japanese clinical practice guidelines for head and neck cancer - 2022 update edited by the Japan society for head and neck cancer
  34. Weekly versus 3‐weekly cisplatin along with radiotherapy for locoregionally advanced non‐nasopharyngeal head and neck cancers: Is the equipoise in literature addressed yet?
  35. Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View
  36. Patient-reported outcome and quality of life research in clinical trials for cancer patients
  37. Chimeric antigen receptor T-cell therapy targeting a MAGE A4 peptide and HLA-A*02:01 complex for unresectable advanced or recurrent solid cancer: protocol for a multi-institutional phase 1 clinical trial
  38. Reply to V. Noronha et al
  39. Phase II study of the efficacy and safety of lenvatinib for anaplastic thyroid cancer (HOPE)
  40. Promising Efficacy of a Third Dose of mRNA SARS-CoV-2 Vaccination in Patients Treated with Anti-CD20 Antibody Who Failed 2-Dose Vaccination
  41. Blowing time ratio and high-resolution manometry to evaluate swallowing function of patients with oral and oropharyngeal cancer
  42. Transition of the PD‑1 occupancy of nivolumab on T cells after discontinuation and response of nivolumab re‑challenge
  43. Impact of baseline tumor burden in patients with differentiated thyroid cancer
  44. Human papillomavirus-related oropharyngeal carcinoma
  45. Safety and immunogenicity of the COVID-19 vaccine BNT162b2 in patients undergoing chemotherapy for solid cancer
  46. Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer (JCOG1008)
  47. Identification of Breast Cancer Stem Cells Using a Newly Developed Long-acting Fluorescence Probe, C5S-A, Targeting ALDH1A1
  48. Systemic therapy for salivary gland malignancy: current status and future perspectives
  49. Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141
  50. A phase I study of LCL161, a novel oral pan‐inhibitor of apoptosis protein (IAP) antagonist, in Japanese patients with advanced solid tumors
  51. Apixaban in Japanese patients with cancer-associated venous thromboembolism: a multi-center phase II trial
  52. Limited increase in antibody titers following mRNA SARS-CoV-2 vaccination for more than 3 years after final dose of anti-CD20 antibody
  53. OUP accepted manuscript
  54. Severe and delayed-onset acneiform eruptions as an adverse reaction to regorafenib
  55. Pan-Asian adaptation of the EHNS–ESMO–ESTRO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with squamous cell carcinoma of the head and neck
  56. Roles of skull base surgery and particle radiotherapy for orbital malignant tumors involving the skull base
  57. Severe and delayed-onset acneiform eruptions as an adverse reaction to regorafenib
  58. Safety and Immunogenicity of the COVID-19 Vaccine BNT162b2 in Patients Undergoing Chemotherapy for Solid Cancer
  59. Docetaxel plus cisplatin for non-squamous cell carcinoma of the head and neck
  60. Minimal Important Difference and Minimal Important Change scores in EORTC QLQ-HN43
  61. Explore the optimal tumor burden for starting lenvatinib for differentiated thyroid cancer
  62. Real-world data of nivolumab for recurrent or metastatic head and neck cancer in Japan
  63. Guidelines for clinical evaluation of anti‐cancer drugs in Japan
  64. Incidence of cancer associated venous thromboembolism in Japan
  65. Interpretation of the results of KEYNOTE-181 Study of Pembrolizumab for Esophageal Cancer
  66. Impact of lung metastases on overall survival in the phase 3 SELECT study of lenvatinib in patients with radioiodine-refractory differentiated thyroid cancer
  67. Correlation of Performance Status and Neutrophil-Lymphocyte Ratio With Efficacy in Radioiodine-Refractory Differentiated Thyroid Cancer Treated With Lenvatinib
  68. Secondary CIC‑rearranged sarcoma responsive to chemotherapy regimens for Ewing sarcoma: A case report
  69. Serum Soluble Interleukin-2 Receptor as a Potential Biomarker for Immune-related Adverse Events
  70. Risk factors for osteoradionecrosis of the jaw in patients with head and neck squamous cell carcinoma
  71. Microsatellite instability-high colorectal cancer patient-derived xenograft models for cancer immunity research
  72. Phase 1 Trial of Anti-PD-1 Ab of Spartalizumab for Japanese Cancer Patients
  73. Regorafenib‑induced exacerbation of chronic immune thrombocytopenic purpura in remission: A case report
  74. Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck
  75. Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)
  76. Relationship between PDGFR expression and the response to pazopanib in intimal sarcoma of the pulmonary artery: A case report
  77. Phase 1 study of Gemcitabine/Nab-paclitaxel/S-1 in patients with unresectable pancreatic cancer (GeNeS1S trial)
  78. Quality of Life in Patients With Hypoparathyroidism After Treatment for Thyroid Cancer
  79. Collaboration with EORTC QOL group and JCOG for PRO/QOL research
  80. Immunotherapy for squamous cell carcinoma of the head and neck
  81. Multi‐institutional Survey of Squamous Cell Carcinoma of the External Auditory Canal in Japan
  82. Safety and Effectiveness of Lenvatinib in 594 Patients with Unresectable Thyroid Cancer in an All-Case Post-Marketing Observational Study in Japan
  83. Long-term Follow-up Data of Nivolumab for Platinum Refractory Head and Neck Cancer in Asia
  84. First line pembrolizumab for recurrent or metastatic head and neck cancer
  85. Ibuprofen gargle for chemo- or Chemoradiotherapy-induced Oral Mucositis: a feasibility study
  86. The relationship between tumor burden and efficacy of nivolumab in head and neck cancer
  87. Nutritional support dependence after curative chemoradiotherapy in head and neck cancer: supplementary analysis of a phase II trial (JCOG0706S1)
  88. Control of Lung Metastases and Colon Polyposis with Lenvatinib Therapy in a Patient with Cribriform-Morular Variant of Papillary Thyroid Carcinoma and an APC Gene Mutation: A Case Study
  89. Nivolumab versus investigator’s choice in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: Efficacy and safety in CheckMate 141 by age
  90. Afatinib vs Placebo as Adjuvant Therapy After Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck
  91. A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition)
  92. Prognostic factors for Lenvatinib in radioiodine-refractory differentiated thyroid cancer (RR-DTC)
  93. PK study of S-1 in patients with renal impairment
  94. Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti‐Epidermal Growth Factor Receptor‐Induced Acne‐Like Rash: A Randomized Left‐Right Comparative Evaluation (APPEARANCE)
  95. A Phase II study of the safety and efficacy of lenvatinib in patients with advanced thyroid cancer
  96. Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 Chemoradiotherapy Trials in Head and Neck Cancer
  97. A Multicenter Phase II Trial of Docetaxel, Cisplatin, and Cetuximab (TPEx) Followed by Cetuximab and Concurrent Radiotherapy for Patients With Local Advanced Squamous Cell Carcinoma of the Head and Neck (CSPOR HN01: ECRIPS Study)
  98. Controversies in relation to neck management in N0 early oral tongue cancer
  99. International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV
  100. Impact of retropharyngeal lymph node dissection in the surgical treatment of hypopharyngeal cancer
  101. Discontinuation of sorafenib can lead to the emergence of FLT3-ITD-positive acute myeloid leukemia
  102. Successful treatment switch from lenvatinib to sorafenib in a patient with radioactive iodine-refractory differentiated thyroid cancer intolerant to lenvatinib due to severe proteinuria
  103. Thrombotic Microangiopathy by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Cancer
  104. Clinical impact of cachexia in unresectable locally advanced head and neck cancer: supplementary analysis of a phase II trial (JCOG0706-S2)
  105. Randomized phase III study to evaluate the value of omission of prophylactic neck dissection for stage I/II tongue cancer: Japan Clinical Oncology Group study (JCOG1601, RESPOND)
  106. Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin
  107. Role of intensive nutrition support and prophylactic percutaneous endoscopic gastrostomy during concomitant chemoradiotherapy for oropharyngeal cancer
  108. CheckMate 141: 1‐Year Update and Subgroup Analysis of Nivolumab as First‐Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer
  109. Nivolumab vs investigator’s choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression
  110. Adapalene gel 0.1% vs. placebo as prophylaxis for anti-EGFR-induced acne-like rash: A randomized left-right comparative evaluation (APPEARANCE).
  111. 3D Culture Represents Apoptosis Induced by Trastuzumab Better than 2D Monolayer Culture
  112. Treatment-emergent hypertension and efficacy in the phase 3 Study of (E7080) lenvatinib in differentiated cancer of the thyroid (SELECT)
  113. Phase II trial of combination treatment with paclitaxel, carboplatin and cetuximab (PCE) as first-line treatment in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (CSPOR-HN02)
  114. Distribution of erlotinib in rash and normal skin in cancer patients receiving erlotinib visualized by matrix assisted laser desorption/ionization mass spectrometry imaging
  115. Three-weekly cisplatin or weekly cisplatin chemoradiotherapy for locally advanced head and neck squamous cell carcinoma—the jury is still out
  116. Immune check point inhibitors for head and neck cancer
  117. Altered fractionation radiotherapy combined with concurrent low-dose or high-dose cisplatin in head and neck cancer: A systematic review of literature and meta-analysis
  118. Prognostic value of ALDH2 polymorphism for patients with oropharyngeal cancer in a Japanese population
  119. Expression of programmed death-1 in sentinel lymph nodes of breast cancer
  120. Optimal use of lenvatinib in the treatment of advanced thyroid cancer
  121. A randomized, open-label, Phase III clinical trial of nivolumab vs. therapy of investigator’s choice in recurrent squamous cell carcinoma of the head and neck: A subanalysis of Asian patients versus the global population in checkmate 141
  122. Prospective Cohort Study of Performance Status and Activities of Daily Living After Surgery for Spinal Metastasis
  123. The validity of the definition of radioiodine refractory thyroid cancer
  124. Japanese Clinical Practice Guideline for Head and Neck Cancer
  125. Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial
  126. Weekly Low‐Dose Versus Three‐Weekly High‐Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non‐Nasopharyngeal Head and Neck Cancer: A Systematic Review and Meta‐Analysis of Aggregate Data
  127. Quality of life and cost-utility of surgical treatment for patients with spinal metastases: prospective cohort study
  128. Exploratory analysis of biomarkers associated with clinical outcomes from the study of lenvatinib in differentiated cancer of the thyroid
  129. Lenvatinib for Anaplastic Thyroid Cancer
  130. Long-term survival of a patient with metastatic melanoma treated with nivolumab and vemurafenib, with the development of vitiligo
  131. The EORTC module for quality of life in patients with thyroid cancer: phase III
  132. Multicenter Phase 2 Study of Cisplatin and 5-Fluorouracil With Concurrent Radiation Therapy as an Organ Preservation Approach in Patients With Squamous Cell Carcinoma of the Cervical Esophagus
  133. Randomized trial of standard pain control with or without gabapentin for pain related to radiation-induced mucositis in head and neck cancer
  134. Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
  135. Quality-of-Life Priorities in Patients with Thyroid Cancer: A Multinational European Organisation for Research and Treatment of Cancer Phase I Study
  136. A prospective, multicenter phase I/II study of induction chemotherapy with docetaxel, cisplatin and fluorouracil (DCF) followed by chemoradiotherapy in patients with unresectable locally advanced esophageal carcinoma
  137. A prospective study on the efficacy of two-dose influenza vaccinations in cancer patients receiving chemotherapy
  138. The combination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in patients with advanced pancreatic cancer
  139. Validity of new methods to evaluate renal function in cancer patients treated with cisplatin
  140. First-line chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma with or without cetuximab: a single institution experience
  141. Treatment outcome of 72 patients with parotid cancer
  142. Subgroup analysis of Japanese patients in a phase 3 study of lenvatinib in radioiodine‐refractory differentiated thyroid cancer
  143. Mediastinal Germ Cell Tumor Exhibiting a Discrepancy between Tumor Markers and Imaging: A Case Study
  144. FDG-PET/contrast-enhanced CT as a post-treatment tool in head and neck squamous cell carcinoma: comparison with FDG-PET/non-contrast-enhanced CT and contrast-enhanced CT
  145. Concomitant chemoradiotherapy for advanced squamous cell carcinoma of the temporal bone
  146. Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial
  147. Phase II trial of chemoradiotherapy with S‐1 plus cisplatin for unresectable locally advanced head and neck cancer ( JCOG 0706)
  148. Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer
  149. Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer
  150. Metabolomics Evaluation of Serum Markers for Cachexia and Their Intra-Day Variation in Patients with Advanced Pancreatic Cancer
  151. Adjuvant treatment for post-operative head and neck squamous cell carcinoma
  152. Effects of Aprepitant on the Pharmacokinetics of Controlled-Release Oral Oxycodone in Cancer Patients
  153. Regulation of MET Kinase Inhibitor Resistance by Copy Number of MET in Gastric Carcinoma Cells
  154. Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III
  155. Randomized Phase II/III Trial of Post-operative Chemoradiotherapy Comparing 3-Weekly Cisplatin with Weekly Cisplatin in High-risk Patients with Squamous Cell Carcinoma of Head and Neck: Japan Clinical Oncology Group Study (JCOG1008)
  156. Prognostic Value of FDG PET Imaging in Patients with Laryngeal Cancer
  157. Rapid improvement of glucagonoma-related necrolytic migratory erythema with octreotide
  158. Role of the medical oncologist in multi-disciplinary treatment for head and neck cancer
  159. Safety profile and efficacy of Chemotherapy with Docetaxel and Cisplatin (DC) for Recurrent or Metastatic Head and Neck Cancer^|^ndash;A Retrospective Analysis in a Single Institution
  160. Therapeutic strategy for advanced laryngeal and hypopharyngeal cancer
  161. Hypothyroidism in patients with colorectal carcinoma treated with fluoropyrimidines
  162. Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line
  163. A phase I study of sorafenib in combination with S-1 plus cisplatin in patients with advanced gastric cancer
  164. A phase I study of tasisulam sodium using an albumin-tailored dose in Japanese patients with advanced solid tumors
  165. Prediction of Glomerular Filtration Rate in Cancer Patients by an Equation for Japanese Estimated Glomerular Filtration Rate
  166. Two cases of melanoma to cervical lymph nodes from an unknown primary site
  167. Radiotherapy for Stage I or II hypopharyngeal carcinoma
  168. Phase II Feasibility Trial of Adjuvant Chemoradiotherapy with 3-weekly Cisplatin for Japanese Patients with Post-operative High-risk Squamous Cell Carcinoma of the Head and Neck
  169. Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line
  170. Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification
  171. A safety profile of sequential therapy for unresectable head and neck cancer: A retrospective analysis in a single institution
  172. Understanding the characteristics of molecular targeting agents for proper usage
  173. Phase I dose-escalating study of panobinostat (LBH589) Administered intravenously to Japanese patients with advanced solid tumors
  174. Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks
  175. Successful neutrophil engraftment by reduced use of granulocyte colony-stimulating factor after allogeneic hematopoietic stem cell transplantation with mycophenolate mofetil for graft-versus-host disease prophylaxis
  176. Management of axitinib (AG-013736)-induced fatigue and thyroid dysfunction, and predictive biomarkers of axitinib exposure: results from phase I studies in Japanese patients
  177. Approaches to encourage broad use of adjuvant chemoradiotherapy for postoperative high-risk patients with squamous cell carcinoma of the head and neck in Japan
  178. Post-operative radiation therapy for locally advanced hypopharyngeal carcinoma
  179. Left atrial extension of metastatic lung tumor via pulmonary vein: report on the first case of Ewing sarcoma
  180. Phase I trial of combination chemotherapy with docetaxel, cisplatin and S-1 (TPS) in patients with locally advanced or recurrent/metastatic head and neck cancer
  181. Future perspectives in head and neck oncology in Japan -Current status and challenges facing clinical trials for head and neck oncology in Japan-
  182. Phase II Trial of Concurrent Chemoradiotherapy with S-1 Plus Cisplatin in Patients with Unresectable Locally Advanced Squamous Cell Carcinoma of the Head and Neck: Japan Clinical Oncology Group Study (JCOG0706)
  183. Systemic Chemotherapy with Cisplatin Plus 5-FU (PF) for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M SCCHN): Efficacy and Safety of a Lower Dose of PF (80/800) at a Single Institution in Japan
  184. Effectiveness of prophylactic percutaneous endoscopic gastrostomy for oropharyngeal cancer patients undergoing concurrent chemoradiotherapy
  185. Nonplatinum-based chemotherapy with irinotecan plus docetaxel for advanced or metastatic olfactory neuroblastoma
  186. Rabeprazole-based eradication therapy for Helicobacter pylori: a large-scale study in Japan
  187. Influence of cure of Helicobacter pylori infection on gastric acidity and gastroesophageal reflux: study by 24-h pH monitoring in patients with gastric or duodenal ulcer