All Stories

  1. Neoadjuvant FOLFOXIRI plus bevacizumab without radiotherapy for high-risk rectal cancer: multicentre phase II trial
  2. Nivolumab for platinum refractory salivary gland cancer
  3. Adverse event profiles and management of cisplatin-based chemoradiotherapy in locally advanced head and neck squamous cell carcinoma: a systematic review
  4. Corrigendum to: A Phase 2 Study of Encorafenib in Combination with Binimetinib in Patients with Metastatic BRAF -Mutated Thyroid Cancer in Japan
  5. Caution Needed Before Adopting Reduced-Dose Elective Neck Irradiation in Head and Neck Cancer: A Response to UPGRADE-RT
  6. Trastuzumab plus docetaxel is an effective treatment option for HER2 positive salivary gland cancer.
  7. Current treatment options and development for anaplastic thyroid cancer (ATC).
  8. Multicenter, open-label, randomized, controlled study to test the utility of electronic patient-reported outcome monitoring in patients with unresectable advanced cancers or metastatic/recurrent solid tumors
  9. Indications for chemoradiotherapy in elderly patients with locally advanced head and neck cancer.
  10. This the updated Japanese guidline for the management of thyroid cancer patients
  11. Retrospective study of definitive therapy for head and neck mucosal melanoma: The RESUME study
  12. Patients with head and neck cancer unfit for cisplatin—what next?
  13. The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer
  14. The european organisation for research and treatment of cancer head and neck cancer module (EORTC QLQ-HN43): Estimates for minimal important difference and minimal important change
  15. Incidence of hypothyroidism after postoperative chemoradiotherapy for head and neck cancer.
  16. Tumor immune microenvironment (TIME) in salivary gand cancer (SGC).
  17. Acute kidney injury impacted the OS for HNSCC patients undergoing postoperative chemoradiotherapy
  18. A risk prediction for cisplatin induced acute kidney injury in JCOG1008
  19. paclitaxel plus cetuximab for double refractory RMHNSCC
  20. Patient-Reported Outcomes in Randomized Controlled Trials for Cancer Conducted in Japan
  21. Targeting Anterior Commissure Involvement with Hyperfractionated Radiotherapy for T1–T2 Squamous Cell Carcinoma of the Glottic Larynx
  22. Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database
  23. Encorafenib/binimetinib should be another treatment option for BRAF mutated thyroid cancer patients.
  24. Post operative treatment for locally advanced squamous cell carcinoma of head and neck.
  25. Long‐term health‐related quality of life in head and neck cancer survivors: A large multinational study
  26. The impact of electronic versus paper-based data capture on data collection logistics and on missing scores in thyroid cancer patients
  27. Different characteristics of the tumor immune microenvironment among subtypes of salivary gland cancer
  28. Summary of Japanese clinical practice guidelines for head and neck cancer - 2022 update edited by the Japan society for head and neck cancer
  29. Weekly versus 3‐weekly cisplatin along with radiotherapy for locoregionally advanced non‐nasopharyngeal head and neck cancers: Is the equipoise in literature addressed yet?
  30. Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View
  31. Patient-reported outcome and quality of life research in clinical trials for cancer patients
  32. Chimeric antigen receptor T-cell therapy targeting a MAGE A4 peptide and HLA-A*02:01 complex for unresectable advanced or recurrent solid cancer: protocol for a multi-institutional phase 1 clinical trial
  33. Reply to V. Noronha et al
  34. Phase II study of the efficacy and safety of lenvatinib for anaplastic thyroid cancer (HOPE)
  35. Promising Efficacy of a Third Dose of mRNA SARS-CoV-2 Vaccination in Patients Treated with Anti-CD20 Antibody Who Failed 2-Dose Vaccination
  36. Blowing time ratio and high-resolution manometry to evaluate swallowing function of patients with oral and oropharyngeal cancer
  37. Transition of the PD‑1 occupancy of nivolumab on T cells after discontinuation and response of nivolumab re‑challenge
  38. Impact of baseline tumor burden in patients with differentiated thyroid cancer
  39. Human papillomavirus-related oropharyngeal carcinoma
  40. Safety and immunogenicity of the COVID-19 vaccine BNT162b2 in patients undergoing chemotherapy for solid cancer
  41. Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer (JCOG1008)
  42. Identification of Breast Cancer Stem Cells Using a Newly Developed Long-acting Fluorescence Probe, C5S-A, Targeting ALDH1A1
  43. Systemic therapy for salivary gland malignancy: current status and future perspectives
  44. Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141
  45. A phase I study of LCL161, a novel oral pan‐inhibitor of apoptosis protein (IAP) antagonist, in Japanese patients with advanced solid tumors
  46. Apixaban in Japanese patients with cancer-associated venous thromboembolism: a multi-center phase II trial
  47. Limited increase in antibody titers following mRNA SARS-CoV-2 vaccination for more than 3 years after final dose of anti-CD20 antibody
  48. OUP accepted manuscript
  49. Severe and delayed-onset acneiform eruptions as an adverse reaction to regorafenib
  50. Pan-Asian adaptation of the EHNS–ESMO–ESTRO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with squamous cell carcinoma of the head and neck
  51. Roles of skull base surgery and particle radiotherapy for orbital malignant tumors involving the skull base
  52. Severe and delayed-onset acneiform eruptions as an adverse reaction to regorafenib
  53. Safety and Immunogenicity of the COVID-19 Vaccine BNT162b2 in Patients Undergoing Chemotherapy for Solid Cancer
  54. Docetaxel plus cisplatin for non-squamous cell carcinoma of the head and neck
  55. Minimal Important Difference and Minimal Important Change scores in EORTC QLQ-HN43
  56. Explore the optimal tumor burden for starting lenvatinib for differentiated thyroid cancer
  57. Real-world data of nivolumab for recurrent or metastatic head and neck cancer in Japan
  58. Guidelines for clinical evaluation of anti‐cancer drugs in Japan
  59. Incidence of cancer associated venous thromboembolism in Japan
  60. Interpretation of the results of KEYNOTE-181 Study of Pembrolizumab for Esophageal Cancer
  61. Impact of lung metastases on overall survival in the phase 3 SELECT study of lenvatinib in patients with radioiodine-refractory differentiated thyroid cancer
  62. Correlation of Performance Status and Neutrophil-Lymphocyte Ratio With Efficacy in Radioiodine-Refractory Differentiated Thyroid Cancer Treated With Lenvatinib
  63. Secondary CIC‑rearranged sarcoma responsive to chemotherapy regimens for Ewing sarcoma: A case report
  64. Serum Soluble Interleukin-2 Receptor as a Potential Biomarker for Immune-related Adverse Events
  65. Risk factors for osteoradionecrosis of the jaw in patients with head and neck squamous cell carcinoma
  66. Microsatellite instability-high colorectal cancer patient-derived xenograft models for cancer immunity research
  67. Phase 1 Trial of Anti-PD-1 Ab of Spartalizumab for Japanese Cancer Patients
  68. Regorafenib‑induced exacerbation of chronic immune thrombocytopenic purpura in remission: A case report
  69. Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck
  70. Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1)
  71. Relationship between PDGFR expression and the response to pazopanib in intimal sarcoma of the pulmonary artery: A case report
  72. Phase 1 study of Gemcitabine/Nab-paclitaxel/S-1 in patients with unresectable pancreatic cancer (GeNeS1S trial)
  73. Quality of Life in Patients With Hypoparathyroidism After Treatment for Thyroid Cancer
  74. Collaboration with EORTC QOL group and JCOG for PRO/QOL research
  75. Immunotherapy for squamous cell carcinoma of the head and neck
  76. Multi‐institutional Survey of Squamous Cell Carcinoma of the External Auditory Canal in Japan
  77. Safety and Effectiveness of Lenvatinib in 594 Patients with Unresectable Thyroid Cancer in an All-Case Post-Marketing Observational Study in Japan
  78. Long-term Follow-up Data of Nivolumab for Platinum Refractory Head and Neck Cancer in Asia
  79. First line pembrolizumab for recurrent or metastatic head and neck cancer
  80. Ibuprofen gargle for chemo- or Chemoradiotherapy-induced Oral Mucositis: a feasibility study
  81. The relationship between tumor burden and efficacy of nivolumab in head and neck cancer
  82. Nutritional support dependence after curative chemoradiotherapy in head and neck cancer: supplementary analysis of a phase II trial (JCOG0706S1)
  83. Control of Lung Metastases and Colon Polyposis with Lenvatinib Therapy in a Patient with Cribriform-Morular Variant of Papillary Thyroid Carcinoma and an APC Gene Mutation: A Case Study
  84. Nivolumab versus investigator’s choice in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: Efficacy and safety in CheckMate 141 by age
  85. Afatinib vs Placebo as Adjuvant Therapy After Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck
  86. A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition)
  87. Prognostic factors for Lenvatinib in radioiodine-refractory differentiated thyroid cancer (RR-DTC)
  88. PK study of S-1 in patients with renal impairment
  89. Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti‐Epidermal Growth Factor Receptor‐Induced Acne‐Like Rash: A Randomized Left‐Right Comparative Evaluation (APPEARANCE)
  90. A Phase II study of the safety and efficacy of lenvatinib in patients with advanced thyroid cancer
  91. Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 Chemoradiotherapy Trials in Head and Neck Cancer
  92. A Multicenter Phase II Trial of Docetaxel, Cisplatin, and Cetuximab (TPEx) Followed by Cetuximab and Concurrent Radiotherapy for Patients With Local Advanced Squamous Cell Carcinoma of the Head and Neck (CSPOR HN01: ECRIPS Study)
  93. Controversies in relation to neck management in N0 early oral tongue cancer
  94. International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV
  95. Impact of retropharyngeal lymph node dissection in the surgical treatment of hypopharyngeal cancer
  96. Discontinuation of sorafenib can lead to the emergence of FLT3-ITD-positive acute myeloid leukemia
  97. Successful treatment switch from lenvatinib to sorafenib in a patient with radioactive iodine-refractory differentiated thyroid cancer intolerant to lenvatinib due to severe proteinuria
  98. Thrombotic Microangiopathy by Lenvatinib for Radioactive Iodine-Refractory Papillary Thyroid Cancer
  99. Clinical impact of cachexia in unresectable locally advanced head and neck cancer: supplementary analysis of a phase II trial (JCOG0706-S2)
  100. Randomized phase III study to evaluate the value of omission of prophylactic neck dissection for stage I/II tongue cancer: Japan Clinical Oncology Group study (JCOG1601, RESPOND)
  101. Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin
  102. Role of intensive nutrition support and prophylactic percutaneous endoscopic gastrostomy during concomitant chemoradiotherapy for oropharyngeal cancer
  103. CheckMate 141: 1‐Year Update and Subgroup Analysis of Nivolumab as First‐Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer
  104. Nivolumab vs investigator’s choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression
  105. Adapalene gel 0.1% vs. placebo as prophylaxis for anti-EGFR-induced acne-like rash: A randomized left-right comparative evaluation (APPEARANCE).
  106. 3D Culture Represents Apoptosis Induced by Trastuzumab Better than 2D Monolayer Culture
  107. Treatment-emergent hypertension and efficacy in the phase 3 Study of (E7080) lenvatinib in differentiated cancer of the thyroid (SELECT)
  108. Phase II trial of combination treatment with paclitaxel, carboplatin and cetuximab (PCE) as first-line treatment in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (CSPOR-HN02)
  109. Distribution of erlotinib in rash and normal skin in cancer patients receiving erlotinib visualized by matrix assisted laser desorption/ionization mass spectrometry imaging
  110. Three-weekly cisplatin or weekly cisplatin chemoradiotherapy for locally advanced head and neck squamous cell carcinoma—the jury is still out
  111. Immune check point inhibitors for head and neck cancer
  112. Altered fractionation radiotherapy combined with concurrent low-dose or high-dose cisplatin in head and neck cancer: A systematic review of literature and meta-analysis
  113. Prognostic value of ALDH2 polymorphism for patients with oropharyngeal cancer in a Japanese population
  114. Expression of programmed death-1 in sentinel lymph nodes of breast cancer
  115. Optimal use of lenvatinib in the treatment of advanced thyroid cancer
  116. A randomized, open-label, Phase III clinical trial of nivolumab vs. therapy of investigator’s choice in recurrent squamous cell carcinoma of the head and neck: A subanalysis of Asian patients versus the global population in checkmate 141
  117. Prospective Cohort Study of Performance Status and Activities of Daily Living After Surgery for Spinal Metastasis
  118. The validity of the definition of radioiodine refractory thyroid cancer
  119. Japanese Clinical Practice Guideline for Head and Neck Cancer
  120. Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial
  121. Weekly Low‐Dose Versus Three‐Weekly High‐Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non‐Nasopharyngeal Head and Neck Cancer: A Systematic Review and Meta‐Analysis of Aggregate Data
  122. Quality of life and cost-utility of surgical treatment for patients with spinal metastases: prospective cohort study
  123. Exploratory analysis of biomarkers associated with clinical outcomes from the study of lenvatinib in differentiated cancer of the thyroid
  124. Lenvatinib for Anaplastic Thyroid Cancer
  125. Long-term survival of a patient with metastatic melanoma treated with nivolumab and vemurafenib, with the development of vitiligo
  126. The EORTC module for quality of life in patients with thyroid cancer: phase III
  127. Multicenter Phase 2 Study of Cisplatin and 5-Fluorouracil With Concurrent Radiation Therapy as an Organ Preservation Approach in Patients With Squamous Cell Carcinoma of the Cervical Esophagus
  128. Randomized trial of standard pain control with or without gabapentin for pain related to radiation-induced mucositis in head and neck cancer
  129. Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
  130. Quality-of-Life Priorities in Patients with Thyroid Cancer: A Multinational European Organisation for Research and Treatment of Cancer Phase I Study
  131. A prospective, multicenter phase I/II study of induction chemotherapy with docetaxel, cisplatin and fluorouracil (DCF) followed by chemoradiotherapy in patients with unresectable locally advanced esophageal carcinoma
  132. A prospective study on the efficacy of two-dose influenza vaccinations in cancer patients receiving chemotherapy
  133. The combination of HLA-B*15:01 and DRB1*15:01 is associated with gemcitabine plus erlotinib-induced interstitial lung disease in patients with advanced pancreatic cancer
  134. Validity of new methods to evaluate renal function in cancer patients treated with cisplatin
  135. First-line chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma with or without cetuximab: a single institution experience
  136. Treatment outcome of 72 patients with parotid cancer
  137. Subgroup analysis of Japanese patients in a phase 3 study of lenvatinib in radioiodine‐refractory differentiated thyroid cancer
  138. Mediastinal Germ Cell Tumor Exhibiting a Discrepancy between Tumor Markers and Imaging: A Case Study
  139. FDG-PET/contrast-enhanced CT as a post-treatment tool in head and neck squamous cell carcinoma: comparison with FDG-PET/non-contrast-enhanced CT and contrast-enhanced CT
  140. Concomitant chemoradiotherapy for advanced squamous cell carcinoma of the temporal bone
  141. Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial
  142. Phase II trial of chemoradiotherapy with S‐1 plus cisplatin for unresectable locally advanced head and neck cancer ( JCOG 0706)
  143. Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer
  144. Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer
  145. Metabolomics Evaluation of Serum Markers for Cachexia and Their Intra-Day Variation in Patients with Advanced Pancreatic Cancer
  146. Adjuvant treatment for post-operative head and neck squamous cell carcinoma
  147. Effects of Aprepitant on the Pharmacokinetics of Controlled-Release Oral Oxycodone in Cancer Patients
  148. Regulation of MET Kinase Inhibitor Resistance by Copy Number of MET in Gastric Carcinoma Cells
  149. Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ-H&N Module, Phase III
  150. Randomized Phase II/III Trial of Post-operative Chemoradiotherapy Comparing 3-Weekly Cisplatin with Weekly Cisplatin in High-risk Patients with Squamous Cell Carcinoma of Head and Neck: Japan Clinical Oncology Group Study (JCOG1008)
  151. Prognostic Value of FDG PET Imaging in Patients with Laryngeal Cancer
  152. Rapid improvement of glucagonoma-related necrolytic migratory erythema with octreotide
  153. Role of the medical oncologist in multi-disciplinary treatment for head and neck cancer
  154. Safety profile and efficacy of Chemotherapy with Docetaxel and Cisplatin (DC) for Recurrent or Metastatic Head and Neck Cancer^|^ndash;A Retrospective Analysis in a Single Institution
  155. Therapeutic strategy for advanced laryngeal and hypopharyngeal cancer
  156. Hypothyroidism in patients with colorectal carcinoma treated with fluoropyrimidines
  157. Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line
  158. A phase I study of sorafenib in combination with S-1 plus cisplatin in patients with advanced gastric cancer
  159. A phase I study of tasisulam sodium using an albumin-tailored dose in Japanese patients with advanced solid tumors
  160. Prediction of Glomerular Filtration Rate in Cancer Patients by an Equation for Japanese Estimated Glomerular Filtration Rate
  161. Two cases of melanoma to cervical lymph nodes from an unknown primary site
  162. Radiotherapy for Stage I or II hypopharyngeal carcinoma
  163. Phase II Feasibility Trial of Adjuvant Chemoradiotherapy with 3-weekly Cisplatin for Japanese Patients with Post-operative High-risk Squamous Cell Carcinoma of the Head and Neck
  164. Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line
  165. Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification
  166. A safety profile of sequential therapy for unresectable head and neck cancer: A retrospective analysis in a single institution
  167. Understanding the characteristics of molecular targeting agents for proper usage
  168. Phase I dose-escalating study of panobinostat (LBH589) Administered intravenously to Japanese patients with advanced solid tumors
  169. Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks
  170. Successful neutrophil engraftment by reduced use of granulocyte colony-stimulating factor after allogeneic hematopoietic stem cell transplantation with mycophenolate mofetil for graft-versus-host disease prophylaxis
  171. Management of axitinib (AG-013736)-induced fatigue and thyroid dysfunction, and predictive biomarkers of axitinib exposure: results from phase I studies in Japanese patients
  172. Approaches to encourage broad use of adjuvant chemoradiotherapy for postoperative high-risk patients with squamous cell carcinoma of the head and neck in Japan
  173. Post-operative radiation therapy for locally advanced hypopharyngeal carcinoma
  174. Left atrial extension of metastatic lung tumor via pulmonary vein: report on the first case of Ewing sarcoma
  175. Phase I trial of combination chemotherapy with docetaxel, cisplatin and S-1 (TPS) in patients with locally advanced or recurrent/metastatic head and neck cancer
  176. Future perspectives in head and neck oncology in Japan -Current status and challenges facing clinical trials for head and neck oncology in Japan-
  177. Phase II Trial of Concurrent Chemoradiotherapy with S-1 Plus Cisplatin in Patients with Unresectable Locally Advanced Squamous Cell Carcinoma of the Head and Neck: Japan Clinical Oncology Group Study (JCOG0706)
  178. Systemic Chemotherapy with Cisplatin Plus 5-FU (PF) for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M SCCHN): Efficacy and Safety of a Lower Dose of PF (80/800) at a Single Institution in Japan
  179. Effectiveness of prophylactic percutaneous endoscopic gastrostomy for oropharyngeal cancer patients undergoing concurrent chemoradiotherapy
  180. Nonplatinum-based chemotherapy with irinotecan plus docetaxel for advanced or metastatic olfactory neuroblastoma
  181. Rabeprazole-based eradication therapy for Helicobacter pylori: a large-scale study in Japan
  182. Influence of cure of Helicobacter pylori infection on gastric acidity and gastroesophageal reflux: study by 24-h pH monitoring in patients with gastric or duodenal ulcer