What is it about?
Kisspeptin is involved in the control of human reproduction bridging the gap between the sex steroid levels; however, studies considering this peptide and infertility are limited. We conducted a review and critical assessment of available evidence considering kisspeptin structure, physiology, function in puberty and reproduction, its role in assisted reproduction treatments, kisspeptin dosage and the impact on KISS1 and GPR54 genes.
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Why is it important?
We conducted a review and critical assessment of available evidence considering kisspeptin structure, physiology, function in puberty and reproduction, its role in assisted reproduction treatments, kisspeptin dosage and the impact on KISS1 and GPR54 genes.
Perspectives
The understanding of the role of kisspeptin may lead to its use as a biomarker in infertility treatments and use in controlled ovarian hyperstimulation.
Dr Bianca Bianco
Faculdade de Medicina do ABC
Read the Original
This page is a summary of: Kisspeptin/GPR54 System: What Do We Know About Its Role in Human Reproduction?, Cellular Physiology and Biochemistry, January 2018, Karger Publishers,
DOI: 10.1159/000493406.
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