What is it about?

Congenital muscular dystrophies are muscle disorders in children,here the case of two sisters with differen CNS imaging is presented and evolution is considered.The fact that they have the same genetic background is of great relevance for considering epigenetic factors.

Featured Image

Why is it important?

Neuroradiological changes in congenital muscular dystrophy are the main feature of hypotonia and prominent muscle atrophy.


Two sisters with a similar mutation had different neuroradiological brain imaging and divergent disease course.

Prof Corrado Angelini
Universita degli Studi di Padova Polo Bibliotecario di Scienze Farmacologia e Scienze Farmaceutiche

Read the Original

This page is a summary of: Divergence of Central Nervous System Involvement in 2 Italian Sisters with Congenital Muscular Dystrophy: A Clinical and Neuroradiological Follow-Up, European Neurology, January 1995, Karger Publishers,
DOI: 10.1159/000117134.
You can read the full text:



The following have contributed to this page