What is it about?

Breast cancer is one of the most common types of cancer diagnosed and the second leading cause of death among women. Breast cancer susceptibility proteins of type 1 and 2 are human tumor suppressor genes. Genetic variations/mutations in these two genes lead to overexpression of human breast tumor suppressor genes (e.g., BRCA1, BRCA2), which triggers uncontrolled duplication of cells in humans.

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Why is it important?

The aim of this study was to analyze some natural compounds or their derivatives as part of the development of strong inhibitors for breast cancer.


α-Hederin, andrographolide, apigenin, asiatic acid, auricular acid, hispolon, sclareol, curcumin, citrinin, and sinularin or their derivatives can be a good source of anticancer agents in breast cancer.

habilitated doctor, chemist Monica BUTNARIU
University of Life Sciences "King Mihai I" from Timisoara

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This page is a summary of: Natural Compounds or Their Derivatives against Breast Cancer: A Computational Study, BioMed Research International, July 2022, Hindawi Publishing Corporation,
DOI: 10.1155/2022/5886269.
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