What is it about?
Breast cancer is one of the most common types of cancer diagnosed and the second leading cause of death among women. Breast cancer susceptibility proteins of type 1 and 2 are human tumor suppressor genes. Genetic variations/mutations in these two genes lead to overexpression of human breast tumor suppressor genes (e.g., BRCA1, BRCA2), which triggers uncontrolled duplication of cells in humans.
Photo by National Cancer Institute on Unsplash
Why is it important?
The aim of this study was to analyze some natural compounds or their derivatives as part of the development of strong inhibitors for breast cancer.
Read the Original
This page is a summary of: Natural Compounds or Their Derivatives against Breast Cancer: A Computational Study, BioMed Research International, July 2022, Hindawi Publishing Corporation, DOI: 10.1155/2022/5886269.
You can read the full text:
Natural Compounds or Their Derivatives against Breast Cancer: A Computational Study
Molecular docking studies were performed using compounds known in the literature to be effective against BRCA1 and BRCA2 and MDR1, with positive control being 5-fluorouracil, an antineoplastic drug as a positive control.
The following have contributed to this page