What is it about?
This letter from 2009 highlights issues with predictive values when disease prevalence is low. Normalizing predictive values to 50% prevalence shows cardiac CTA has a high positive predictive value, but negative results should not rule out disease.
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Why is it important?
Normalizing predictive values is important for meaningful interpretation and comparison across studies. Highlights the need for cautious interpretation of cardiac CTA's negative predictive value despite high specificity.
Read the Original
This page is a summary of: Detection of myocardial infarction by CT angiography, Heart, June 2009, BMJ,
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