What is it about?
This paper is about IscR, an Fe-S cluster-containing transcription factor and its roles in pathogenesis of Vibrio vulnificus.
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Why is it important?
IscR is a global regulator which contributes to the overall success in the pathogenesis of Vibrio vulnificus by regulating the expression of various virulence and survival genes. Furthermore, since IscR expression is induced by exposure of the pathogen to host cells, this transcription factor may play an essential role during infection.
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This page is a summary of: IscR Is a Global Regulator Essential for Pathogenesis of Vibrio vulnificus and Induced by Host Cells, Infection and Immunity, November 2013, ASM Journals,
DOI: 10.1128/iai.01141-13.
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