What is it about?
Most bacteriophages isolated to date have a very narrow host range, a characteristic that may hinder their scope of applications. We have developed methods for the isolation of bacteriophages with very broad host ranges.
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Why is it important?
Our work is the first to provide a method for isolating polyvalent bacteriophages that have a similar efficiency of plating on all hosts. This expands the scope of potential applications and is likely to provide new insights into bacteriophage ecology.
Perspectives
Polyvalent bacteriophages have important implications for large-scale bacteriophage production, microbiome engineering, and environmental gene delivery. One of the major challenges for phage therapy or biocontrol has been host range. The methods we have developed help address this problem.
Dr Jacques Mathieu
Rice University
Read the Original
This page is a summary of: Isolation of Polyvalent Bacteriophages by Sequential Multiple-Host Approaches, Applied and Environmental Microbiology, November 2015, ASM Journals,
DOI: 10.1128/aem.02382-15.
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