Characterization of the Complete Nucleotide Sequences of IMP-4-Encoding Plasmids, Belonging to Diverse Inc Families, Recovered from Enterobacteriaceae Isolates of Wildlife Origin

  • Monika Dolejska, Costas C. Papagiannitsis, Matej Medvecky, Lenka Davidova-Gerzova, Adam Valcek
  • Antimicrobial Agents and Chemotherapy, February 2018, ASM Journals
  • DOI: 10.1128/aac.02434-17

Sequences of IMP-4-encoding plasmids

What is it about?

The complete nucleotide sequences of six IMP-4-encoding plasmids recovered from Enterobacteriaceae of wildlife origin were characterized. Sequencing data showed that plasmids of different incompatibility groups (IncM, IncI1, IncF, and nontypeable [including an IncX5_2 and two pPrY2001-like]) carried the blaIMP-4-carrying integrons, In809 or In1460. Most of the plasmids carried mph(A) region, and chrA-like, aac(3)-IId and blaTEM-1b genes. Finally, plasmid analysis revealed the involvement of two different, IS26- and Tn1696-associated, mechanisms in the mobilization of IMP-4-encoding integrons.

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The following have contributed to this page: Constantinos C Papagiannitsis