What is it about?
The focus of this work is testing the small molecule drug tilorone against the mouse infection model for ebola. We also provide some in vitro data on this old drug.
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Why is it important?
Ebola has a high fatality rate and there are currently no approved drugs or vaccines. The compound is a known antiviral approved in Russia and several other countries. It is already used against some viruses.
Perspectives
We discovered tilorone using machine learning in 2015. This publication suggests the molecule could be worth further evaluation.
Dr Sean Ekins
Collaborations in Chemistry
Read the Original
This page is a summary of: Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection, Antimicrobial Agents and Chemotherapy, November 2017, ASM Journals,
DOI: 10.1128/aac.01711-17.
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Contributors
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