All Stories

  1. Repurposing Clinical Candidates for Nipah and Hendra Viruses
  2. Viral Disruption of Blood–Testis Barrier Precedes Testicular Infection
  3. Efficacy of Polyphenylene Carboxymethylene (PPCM) Gel at Protecting Type I Interferon Receptors Knockout Mice from Intravaginal Ebola Virus Challenge
  4. Efficacy and Immunogenicity of a Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine in Cynomolgus Macaques
  5. Comparison of Routes of Administration, Frequency, and Duration of Favipiravir Treatment in Mouse and Guinea Pig Models of Ebola Virus Disease
  6. Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes
  7. Pteropus vampyrus TRIM40 Is an Interferon-Stimulated Gene That Antagonizes RIG-I-like Receptors
  8. The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection
  9. Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities
  10. Hydrogen Sulfide Ameliorates SARS-CoV-2-Associated Lung Endothelial Barrier Disruption
  11. Hydrogen Sulfide Ameliorates SARS-CoV-2–Associated Lung Endothelial Barrier Disruption
  12. Differences in Genetic Diversity of Mammalian Tick-Borne Flaviviruses
  13. Powassan Virus Induces Structural Changes in Human Neuronal Cells In Vitro and Murine Neurons In Vivo
  14. Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly
  15. The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
  16. Tilorone-Dihydrochloride Protects against Rift Valley Fever Virus Infection and Disease in the Mouse Model
  17. Nipah virus Bangladesh infection elicits organ-specific innate and inflammatory responses in the marmoset model
  18. Polyphenylene carboxymethylene (PPCM) microbicide repurposed as antiviral against SARS-CoV-2. Proof of concept in primary human undifferentiated epithelial cells
  19. Recent advances in combating Nipah virus
  20. Rift Valley fever virus 78kDa envelope protein attenuates virus replication in macrophage-derived cell lines and viral virulence in mice
  21. STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV)
  22. Author Correction: Spike mutation D614G alters SARS-CoV-2 fitness
  23. Discovery of a novel highly potent broad-spectrum heterocyclic chemical series of arenavirus cell entry inhibitors
  24. Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition
  25. Inhibition of innate immune response ameliorates Zika virus-induced neurogenesis deficit in human neural stem cells
  26. Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
  27. Targeted disruption of pi–pi stacking in Malaysian banana lectin reduces mitogenicity while preserving antiviral activity
  28. SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species
  29. Spike mutation D614G alters SARS-CoV-2 fitness
  30. Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig
  31. SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts
  32. Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors
  33. VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection
  34. Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism
  35. SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors
  36. Polyphenylene carboxymethylene (PPCM) in vitro antiviral efficacy against Ebola virus in the context of a sexually transmitted infection
  37. Repurposing Quinacrine against Ebola Virus Infection In Vivo
  38. Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity
  39. Henipavirus infection of the central nervous system
  40. Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir
  41. A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice
  42. Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines
  43. Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing
  44. Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters
  45. Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription
  46. Experimental Infection of Syrian Hamsters With Aerosolized Nipah Virus
  47. Favipiravir (T-705) protects against Nipah virus infection in the hamster model
  48. Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model
  49. Attenuation and protective efficacy of Rift Valley fever phlebovirus rMP12-GM50 strain
  50. Finding an old drug that works against ebola
  51. Recent advances in the development of antiviral therapeutics for Rift Valley fever virus infection
  52. Contribution of Human Lung Parenchyma and Leukocyte Influx to Oxidative Stress and Immune System-Mediated Pathology following Nipah Virus Infection
  53. The host ubiquitin system promotes Ebola virus replication
  54. Efficient and Robust Paramyxoviridae Reverse Genetics Systems
  55. Cross-neutralisation of viruses of the tick-borne encephalitis complex following tick-borne encephalitis vaccination and/or infection
  56. Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses
  57. The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response
  58. Antiviral effect of ranpirnase against Ebola virus
  59. Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR
  60. N-Glycans on the Rift Valley Fever Virus Envelope Glycoproteins Gn and Gc Redundantly Support Viral Infection via DC-SIGN
  61. Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway
  62. ISG15 deficiency and increased viral resistance in humans but not mice
  63. Optimized P2A for reporter gene insertion into Nipah virus results in efficient ribosomal skipping and wild-type lethality
  64. Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine
  65. Cytokine response in mouse bone marrow derived macrophages after infection with pathogenic and non-pathogenic Rift Valley fever virus
  66. Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L Segments
  67. Evidence for Ubiquitin-Regulated Nuclear and Subnuclear Trafficking among Paramyxovirinae Matrix Proteins
  68. Timing of Galectin-1 Exposure Differentially Modulates Nipah Virus Entry and Syncytium Formation in Endothelial Cells
  69. Evidence for henipavirus spillover into human populations in Africa
  70. Efficient Reverse Genetics Reveals Genetic Determinants of Budding and Fusogenic Differences between Nipah and Hendra Viruses and Enables Real-Time Monitoring of Viral Spread in Small Animal Models of Henipavirus Infection
  71. Multiplexed Digital mRNA Profiling of the Inflammatory Response in the West Nile Swiss Webster Mouse Model
  72. Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names
  73. Role of Protein Phosphatase 1 in Dephosphorylation of Ebola Virus VP30 Protein and Its Targeting for the Inhibition of Viral Transcription
  74. Bunyaviruses: Hantavirus and Others
  75. Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever
  76. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA
  77. Modeling Pre-Existing Immunity to Adenovirus in Rodents: Immunological Requirements for Successful Development of a Recombinant Adenovirus Serotype 5-Based Ebola Vaccine
  78. Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes
  79. Rift Valley fever virus MP-12 vaccine encoding Toscana virus NSs retains neuroinvasiveness in mice
  80. Rift Valley Fever Virus and Hemorrhagic Fever
  81. The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains
  82. Characterization of Rift Valley Fever Virus MP-12 Strain Encoding NSs of Punta Toro Virus or Sandfly Fever Sicilian Virus
  83. A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion
  84. Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae
  85. Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol
  86. Genetic Subpopulations of Rift Valley Fever Virus Strains ZH548 and MP-12 and Recombinant MP-12 Strains
  87. Detection of Severe Fever with Thrombocytopenia Syndrome Virus by Reverse Transcription-Cross-Priming Amplification Coupled with Vertical Flow Visualization
  88. Recent progress in henipavirus research: Molecular biology, genetic diversity, animal models
  89. Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein
  90. The Dominant-Negative Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR Increases the Efficacy of Rift Valley Fever Virus MP-12 Vaccine
  91. Chemotactic and Inflammatory Responses in the Liver and Brain Are Associated with Pathogenesis of Rift Valley Fever Virus Infection in the Mouse
  92. An Assembly Model of Rift Valley Fever Virus
  93. A Single Sublingual Dose of an Adenovirus-Based Vaccine Protects against Lethal Ebola Challenge in Mice and Guinea Pigs
  94. Recombinant Rift Valley fever vaccines induce protective levels of antibody in baboons and resistance to lethal challenge in mice
  95. Inactivated or Live-Attenuated Bivalent Vaccines That Confer Protection against Rabies and Ebola Viruses
  96. Differential cytokine responses from primary human Kupffer cells following infection with wild-type or vaccine strain yellow fever virus
  97. T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture
  98. Ubiquitin-Regulated Nuclear-Cytoplasmic Trafficking of the Nipah Virus Matrix Protein Is Important for Viral Budding
  99. A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB
  100. Oligomerization of Uukuniemi virus nucleocapsid protein
  101. A replication-incompetent Rift Valley fever vaccine: Chimeric virus-like particles protect mice and rats against lethal challenge
  102. A broad-spectrum antiviral targeting entry of enveloped viruses
  103. Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection
  104. Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening
  105. Single-particle cryo-electron microscopy of Rift Valley fever virus
  106. Phage Tailspike Proteins withβ-Solenoid Fold as Thermostable Carbohydrate Binding Materials
  107. A catalytically and genetically optimized β-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics
  108. Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus
  109. Three-Dimensional Organization of Rift Valley Fever Virus Revealed by Cryoelectron Tomography
  110. An Intersubunit Active Site between Supercoiled Parallel β Helices in the Trimeric Tailspike Endorhamnosidase of Shigella flexneri Phage Sf6
  111. Establishment and characterization of plasmid-driven minigenome rescue systems for Nipah virus: RNA polymerase I- and T7-catalyzed generation of functional paramyxoviral RNA
  112. Folding and Stability of the Leucine-rich Repeat Domain of Internalin B from Listeria monocytogenes
  113. The Tailspike Protein of Shigella Phage Sf6: A STRUCTURAL HOMOLOG OF SALMONELLA PHAGE P22 TAILSPIKE PROTEIN WITHOUT SEQUENCE SIMILARITY IN THE  -HELIX DOMAIN
  114. Stability and Folding of Internalin B - A Biophysical Characterization