Replication-coupled histone H3.1 deposition determines nucleosome composition and heterochromatin dynamics during Arabidopsis seedling development

What is it about?

Clustering of repetitive heterochromatic loci into chromocenter structures is an important determinant of nuclear organization. Here we analyzed the changes at the level of the nucleosome that contribute to the formation of chromocenter structures during seedling growth. We find changes in the distribution of specific histone variants and post-translational modifications, which are hallmarks of heterochromatin, and that histone deposition during replication promotes chromocenter formation.

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