What is it about?
Rfx1 is a trancription factor. Rfx1 has bipartite functions in the control of the expression of genes in cell division and chitin metabolism, not only as a transcriptional repressor, but also as a transcriptional activator. The expression of CDA2 and CDA1, two chitin deacetylase genes, was down-regulated greatly in the null mutant. Rfx1 is involved in fungal development and virulence by affecting cell division and cell wall integrity. Bleomycin not only functions in DNA, but also in cell wall.
Featured Image
Why is it important?
Expand our knowledges about the roles of the regulatory factor X protein. In the past, Rfx1 is consideed as a transcription factor involved in DNA integrity. Now, we confirmed that Rfx1 also has an important role in cell wall integrity.
Perspectives
RFX1 has important roles in fungal growth, conidiation, conidial morphology, appressorium turgor production, virulence on plant, cell division, and sensitivity to UV light, DNA‐damaging agents, and cell wall‐perturbing compounds. Combining with other transcription factors, Rfx1 could supply a total perspective about cell wall formation, conidial differentiation, and pathogenicity in the fungus.
Dr Jianping Lu
Zhejiang University
Read the Original
This page is a summary of: The regulatory factor X protein MoRfx1 is required for development and pathogenicity in the rice blast fungusMagnaporthe oryzae, Molecular Plant Pathology, September 2016, Wiley,
DOI: 10.1111/mpp.12461.
You can read the full text:
Contributors
The following have contributed to this page
