What is it about?

This article introduces a new method to define gating of an anion channel and a drug binding site.

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Why is it important?

This article introduces a new method to define gating of an anion channel and a drug binding site.

Perspectives

Chloride-dependent zinc regulation of an ion channel can be used to define gating rearrangements of the pore-lining pathway.

Gary Wang

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This page is a summary of: External Zn2+binding to cysteine-substituted cystic fibrosis transmembrane conductance regulator constructs regulates channel gating and curcumin potentiation, FEBS Journal, June 2016, Wiley,
DOI: 10.1111/febs.13752.
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