What is it about?
We present an broad overview of compounds with potential to treat Alzheimer's disease by means of the alternative strategy approached in this work, i.e., allosteric mechanism with key targets related to such neurodegenerative disease. Their structures and biological activities are described along with several literature indications.
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Why is it important?
This review is important because it helps to contributing to further research and development of new drug candidates to treat AD. Especifically, it fulfills an evident need for gathering information on the topic of allosteric modulation of AD-targets, which is a promissing therapeutic strategy.
Read the Original
This page is a summary of: Allosteric Modulators of Potential Targets Related to Alzheimer's Disease: a Review, ChemMedChem, August 2019, Wiley, DOI: 10.1002/cmdc.201900299.
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