What is it about?

Prostaglandins are essential for the programmed termination of pregnancies. The comparison of results in the use of misoprostol or dinoprostone in a homogeneous group of patients, allows the choice of the preparation that best fits the conditions of the patients.

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Why is it important?

In developed countries, approximately 20% of pregnancies end with induction procedures. Currently, there are prostaglandin preparations with exclusive indication for cervical ripening in the induction of labor. Doses are adjusted for this indication and their efficacy and side effects are similar. This work is important for the adjusted dosage of prostaglandins and for the homogeneity of the group studied. These are primiparous pregnant women in their 41st week, without risk factors or major complications of pregnancy.

Perspectives

I would like with this article, that colleagues consider that any of the prostaglandins, when the doses are adjusted, have similar effects in cervical ripening

José Manuel Campillos
Hospital Universitario Miguel Servet de Zaragoza

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This page is a summary of: Low‐dose vaginal misoprostol versus vaginal dinoprostone insert for induction of labor beyond 41st week: a randomized trial, Acta Obstetricia Et Gynecologica Scandinavica, February 2019, Wiley,
DOI: 10.1111/aogs.13556.
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