What is it about?

Recurrent pregnancy loss (RPL) is defined as two or more losses of pregnancy at any point. It is a common problem with many possible causes and side-effects. Previous studies have shown a link bewteen RPL and a higher risk of preterm birth, premature rupture of membrane, and low birth weight. While these associations are well established, there is controversy as to whether RPL increases the risk of birth defects and congenital diseases. This study analysed data from over 1000 pregnancies. New links were found between RPL and and incrreases risk of placental adhesion and utrine infection. However, no association was found bewteen RPL and birth defects or chromosomal abnormalities.

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Why is it important?

These results can help reduce anxiety around pregnancy and childbirth for RPL patients.

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This page is a summary of: Adverse pregnancy and perinatal outcome in patients with recurrent pregnancy loss: Multiple imputation analyses with propensity score adjustment applied to a large‐scale birth cohort of the Japan Environment and Children’s Study, American Journal of Reproductive Immunology, December 2018, Wiley,
DOI: 10.1111/aji.13072.
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