What is it about?
This article builds on our previous published work where we showed that a long surface structure of Group A Streptococcus (known as a pilus) can be produced on the surface of the harmless bacterium Lactococcus lactis. These bacteria were used to vaccinate mice which become immune against bacterial infection.
Photo by CDC on Unsplash
Why is it important?
The work describes a novel vaccine candidate against group A Streptococcus which causes a range of diseases in humans, including skin and soft tissue infections, toxic shock and rheumatic fever.
Read the Original
This page is a summary of: Expanding strain coverage of a group A Streptococcus pilus–expressing Lactococcus lactis mucosal vaccine, Immunology and Cell Biology, April 2023, Wiley, DOI: 10.1111/imcb.12643.
You can read the full text:
The following have contributed to this page