Genome-Wide Analysis of Alternative Splicing Landscapes Modulated during Plant-Virus Interactions in Brachypodium distachyon

What is it about?

Alternative splicing is a key biological process in eukaryotes. In this study, using RNA-sequencing and bioinformatics tools, we have shown the genome-wide alternative splicing changes occurring during plant disease caused by viruses.

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Why is it important?

We have identified alternative splicing events in several disease resistance genes, transcription factors and protein kinases that were previously unknown. Importantly, we found differential splicing in splicing factors that could potentially influence the global splicing homeostasis during plant disease.