What is it about?
We describe the LungMAP portal wherein researchers can now access various multimodal data for systems-level exploration of the lung. We provide details of the lungmap.net website, which centralizes and standardizes information across broad lung research efforts. We have aggregated a diverse collection of single-cell atlases for multiple species (human, rhesus, mouse), to enable consistent queries across technologies, cohorts, age, disease and drug treatment.
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Why is it important?
An improved understanding of the human lung necessitates advanced systems models informed by an ever-increasing repertoire of molecular omics, cellular, imaging and pathological datasets. To centralize and standardize information across broad lung research efforts we expanded the LungMAP.net website into a gateway portal.
Perspectives
Data coordination and management is important in studying human organs and associated diseases. In this work, we brought together data that are standardized across species and technologies using harmonized data and metadata models that leverage recent advances including those from the Human Cell Atlas, diverse ontologies, and the LungMAP CellCards initiative.
Surya Prasath
Cincinnati Children's Hospital Medical Center
Read the Original
This page is a summary of: LungMAP Portal Ecosystem: Systems-Level Exploration of the Lung, December 2021, Cold Spring Harbor Laboratory Press,
DOI: 10.1101/2021.12.05.471312.
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