What is it about?
DNA replication in E.coli is initiated by DnaA protein.In the absence of this initiator protein, the replication can be restarted by gamma ray irradiation at low doses. The starting sites are distributed stochastically. Other mutants such as dnaB failed to initiate in the same conditions.
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Why is it important?
This publication demonstrated ,for the first time ,the phenomenon of so called "stable replication "named later by Lark & Kogoma.
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This page is a summary of: DNA replication in the halophilic archaeobacterium Haloferax volcanii in the absence of protein synthesis, Journal of General Microbiology, November 1993, Society for General Microbiology,
DOI: 10.1099/00221287-139-11-2543.
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