What is it about?
Wnt signaling stimulates bone formation through activation of glucose metabolism in osteoblasts.
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Why is it important?
This is the first genetic demonstration of glucose metabolism in Wnt-induced bone formation.
Perspectives
A comprehensive understanding of cellular metabolism in bone may uncover potential targets for novel bone therapies.
FANXIN LONG
Children's Hospital of Philadelphia
Read the Original
This page is a summary of: Increased glycolysis mediates Wnt7b-induced bone formation, The FASEB Journal, July 2019, Federation of American Societies For Experimental Biology (FASEB),
DOI: 10.1096/fj.201900201rr.
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