What is it about?
Spaceflight that results in microgravity provides an idealized condition to simultaneously unload all muscle groups in otherwise healthy individuals. With this model, this study reveals the molecular response of different types of shoulder muscles to microgravity.
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Why is it important?
Our findings first demonstrate that shoulder muscle response to microgravity is muscle-type specific and have important implications for clinical conditions of muscle unloading and long-duration spaceflight.
Perspectives
By highlighting the differential sensitivity and the dynamics of different types of shoulder muscles to microgravity, we hope that this study will inspire the development of muscle type-specific therapies for relevant clinical conditions and preventive measures for long-term spaceflight.
Hua Shen
Washington University in Saint Louis
Read the Original
This page is a summary of: Effects of spaceflight on the muscles of the murine shoulder, The FASEB Journal, August 2017, Federation of American Societies For Experimental Biology (FASEB),
DOI: 10.1096/fj.201700320r.
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