What is it about?

Bed-wetting is common in children and happens more often in children who have obstructive sleep apnea. We studied children suspected of having obstructive sleep apnea who were having sleep studies and asked them about bed-wetting. We wanted to understand why children with obstructive sleep apnea are more likely to have bed-wetting; understanding why these two sleep problems often happen together would help us learn about the underlying problems causing bed-wetting and obstructive sleep apnea. What we found was that obstructive sleep apnea was not worse in children with enuresis but children with enuresis did have more pauses in breathing that came from their brain sending less signals to breathe (central apnea and hypoppnea) as well as an increase, rather than the expected decrease, in heart rate across the night. These findings suggest that autonomic control, the system in the brain that regulates automatic body functions such as heart rate, breathing pattern, and temperature regulation, is set differently in some children which predisposes them to both nocturnal enuresis and bed-wetting.

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Why is it important?

This is important because both of these problems are hard for children and their families and our current treatments for both bed-wetting and obstructive sleep apnea are limited. If we better understand the underlying causes of these sleep problems, we can look at new waves of providing treatment and ways to prevent them from happening.

Perspectives

The results from this study give us a new way to think about bed-wetting and obstructive sleep apnea. The autonomic control is a system deep in our brain that controls things like our heart rate and how easy we are woken from sleep. Differences autonomic control may explain why bed-wetting and obstructive sleep happen can happen together and why treatments for obstructive sleep apnea that do not change autonomic control do not fix bed-wetting. This gives us new options to consider for treatment that may help both bed-wetting and obstructive sleep apnea.

Dr Joanna E MacLean
University of Alberta

Read the Original

This page is a summary of: Nocturnal enuresis in children is associated with differences in autonomic control, SLEEP, November 2018, Oxford University Press (OUP),
DOI: 10.1093/sleep/zsy239.
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