What is it about?

The cellular prion protein (PrPC) is involved in fatal neurological diseases, but its physiologic fuction is still unknown. By using a heart experimental paradigm, here we show that PrPC contributes to cell defences against oxidative stress.

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Why is it important?

Our finding is important becaise it increases our knowledge on the biology of the prion protein.

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This page is a summary of: The cellular prion protein counteracts cardiac oxidative stress, Cardiovascular Research, August 2014, European Society of Cardiology,
DOI: 10.1093/cvr/cvu194.
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