What is it about?
Beyond what is currently known that liver cirrhosis promotes diabetes, this study provides a new evidence on temporal relationship by which diabetes also promotes the development of liver cirrhosis and its decompensation in patients with chronic hepatitis B, which could infer a causal relationship, rather than only association.
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Why is it important?
Chronic hepatitis B patients who develop diabetes during follow-up are at an increased risk of cirrhosis and its decompensation over time and should receive active glycemic control to improve outcome.
Perspectives
The development of diabetes in chronic hepatitis B patients advances the stage of liver disease with the fibrosis progression, development of ascites and variceal bleeding as well as hepatic coma. Thus, active prevention of diabetes with lifestyle modification and optimal glycemic control in those with diabetes is important to improve the outcome of these patients.
Dr Yi-Wen Huang
Cathay General Hospital Medical Center
Read the Original
This page is a summary of: Increased Risk of Cirrhosis and Its Decompensation in Chronic Hepatitis B Patients With Newly Diagnosed Diabetes: A Nationwide Cohort Study, Clinical Infectious Diseases, September 2013, Oxford University Press (OUP),
DOI: 10.1093/cid/cit603.
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