What is it about?
Gestational diabetes mellitus (GDM) is a form of glucose intolerance recognised during pregnancy. Although some intrinsic risk factors have been identified, the environmental risk factors remain unclear. In this study 16,955 Japanese woman had theid blood tested for levels of lead and cadmium - two known environmental contaminants. Although concentrations of these toxic metals were higher in women with GDM, the levels were not significantly different to women without GDM. This held true irrespective of pregnancy outcomes.
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Why is it important?
GDM increases the risk of developing type 2 diabetes mellitus, obesity and metabolic syndrome - in both mother and child. This study indicates that there was a lack of assoication bewteen concentrations of toxic metals in the enviroment and development of GDM during pregnancy. More studies are required to understand environmental risks.
Read the Original
This page is a summary of: Association of prenatal maternal blood lead levels with birth outcomes in the Japan Environment and Children’s Study (JECS): a nationwide birth cohort study, International Journal of Epidemiology, November 2020, Oxford University Press (OUP),
DOI: 10.1093/ije/dyaa162.
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