Discovery of "IgM Memory" B cells

What is it about?

This is the first report that IgM B cells, previously thought of as naive cells that haven't reacted to antigen yet, are not all naive. Some specialised cells show evidence of activation that is normally seen in memory cells. Later evidence since this publication leads us to suspect that these cells may be responding to infectious challenge in a different manner, without the direct help from T cells.

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