Outcome of Patients with Mixed Aortic Valve Disease Undergoing Transfemoral Aortic Valve Replacement

What is it about?

Transfemoral aortic valve replacement (TAVR) in severe aortic stenosis (AS) has been shown to be superior to surgical aortic valve replacement in patients at high and intermediate surgical risk . Data on outcome of TAVR in mixed aortic valve disease however are scarce.

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Why is it important?

Current guidelines give a class IIb indication for TAVR in severe AS and moderate but not severe coexisting AR, emphasizing treatment determined by the predominant lesion. Data on acute and long-term outcome in patients undergoing TAVR with new generation devices for mixed aortic valve disease are missing. This fisrt data on TAVR in patients with mixed aortic valve diseasedemostrates comparable 30 days, 12 and 24 months clinical outcome compared to patients undergoing TAVR for severe aortic stenosis.

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