What is it about?

The hepatoprotective role of two natural compounds (glycyrrhizin and omega-3 fatty acids) against thioacetamide-induced liver fibrosis in rats and the molecular mechanism of this role through toll-like receptor 4

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Why is it important?

The effect of these natural compounds on TLR-4 is newly illustrated. TLR-4 is one of the crucial pathways in regulation of inflammation. Moreover, these are natural compounds safe and available to prevent liver fibrosis.

Perspectives

I hope this article attracts more interest in the natural compounds and their anti-fibrotic and anti-inflammatory roles.

Dr Nada Fawzy Abo El-Magd
Mansoura University

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This page is a summary of: Glycyrrhizin and Omega-3 fatty acids have hepatoprotective roles through toll-like receptor-4, Egyptian Journal of Basic and Applied Sciences, September 2019, Taylor & Francis,
DOI: 10.1080/2314808x.2019.1669111.
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