What is it about?

Design, synthesis, and biological evaluation of new chemical compounds (called thiadiazolo-acridine derivatives) as potential anticancer drugs, particularly against breast cancer.

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Why is it important?

It is important because it contributes to the ongoing search for better and safer cancer treatments, particularly for breast cancer, which remains one of the leading causes of cancer-related deaths in women worldwide.

Perspectives

The successful synthesis of N-(5-((acridin-9-ylamino)methyl)-1,3,4-thiadiazol-2-yl)-substituted benzamides demonstrates the potential of thiadiazolo-acridine scaffolds as promising candidates in anticancer drug development, particularly against breast cancer.

Dr Hemalatha Kanagarajan
Saveetha college of pharmacy

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This page is a summary of: Synthesis, molecular docking, and In-vitro cytotoxic evaluation of Thiadiazolo-acridines analogues as anti-cancer agents, Analytical Chemistry Letters, May 2025, Taylor & Francis,
DOI: 10.1080/22297928.2025.2472311.
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