What is it about?

Immature or partial mature structure induce non-neutralizing antibodies more oftenly than mature particles.

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Why is it important?

Vaccine protection and the correlates with neutralizing antibodies might involve the types and structures of viruses used.

Perspectives

Understanding the memory B cell development might be the key to answer the question

Dr Day-yu Chao
national chung-hsing university

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This page is a summary of: Does structurally-mature dengue virion matter in vaccine preparation in post-Dengvaxia era?, Human Vaccines & Immunotherapeutics, August 2019, Taylor & Francis,
DOI: 10.1080/21645515.2019.1643676.
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