How atomic force microscopy is being used to investigate drug delivery vehicles
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What is it about?
We summarise our perspectives on the use of atomic force microscopy (AFM) to characterise systems that target the delivery of drugs, such as nanoparticles and nanofibres. Papers selected from 2015-2018 are reviewed following a detailed introduction to the AFM technique. The main review sections are ordered into areas of increasing AFM complexity: imaging/particle sizing, surface roughness/quantitative analysis of images and analysis of force curves (to extract nanoindentation and adhesion data).
Why is it important?
Advances in nanomedicine are dependent on developments in the characterisation of nanoscale drug delivery systems. This paper scopes the field and includes comments from the authors whom have used AFM for many years.
The following have contributed to this page: Dr James R Smith and Dimitrios A. Lamprou