What is it about?
The metabolic shift between respiration and fermentation pathways in yeast is explained according to a system dynamics modelling approach providing new insights in the phenomenon of sugar induced cell death
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Why is it important?
A bridge between yeast and cancer metabolism and the clarification of the ATP energy balance in association to sugar uptake and cell death induction
Perspectives
This paper deserves attention because it explains the link between nutritional conditions, cell metabolism and death according to a system dynamics view of glycolysis pathway
Prof. Stefano Mazzoleni
Universita degli Studi di Napoli Federico II
Read the Original
This page is a summary of: Revisiting the Crabtree/Warburg effect in a dynamic perspective: a fitness advantage against sugar-induced cell death, Cell Cycle, March 2018, Taylor & Francis,
DOI: 10.1080/15384101.2018.1442622.
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