What is it about?

One new depsidone, polyanthadepsidone A (1), together with four known compounds were isolated from the dichloromethane extract of the leaves of Garcinia polyantha. The structures of all compounds were determined by comprehensive analyses of their 1D and 2D NMR and EI mass spectral data.

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Why is it important?

All the isolates exhibited suppressive effect on phagocytosis response upon activation with serum opsonised zymosan in the IC50 range of 4.5–23.80 μM, tested in vitro for oxidative burst studies of whole blood.

Perspectives

Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. This article also lead to rare disease groups contacting me and ultimately to a greater involvement in rare disease research.

Professor Alain Meli Lannang

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This page is a summary of: A new depsidone derivative from the leaves of Garcinia polyantha, Natural Product Research, September 2017, Taylor & Francis, DOI: 10.1080/14786419.2017.1378201.
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